Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun 20;12(12):e028974.
doi: 10.1161/JAHA.122.028974. Epub 2023 Jun 10.

Is Hypertrophic Cardiomyopathy Always a Familial and Inherited Disease?

Jiri Bonaventura  1   2 , Ethan J Rowin  1 , Martin S Maron  1 , Barry J Maron  1
Affiliations

Is Hypertrophic Cardiomyopathy Always a Familial and Inherited Disease?

Jiri Bonaventura et al. J Am Heart Assoc. .
No abstract available

Keywords: familial; genetics; hypertrophic cardiomyopathy; inheritance.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Four study pedigrees demonstrating the nonfamilial form of hypertrophic cardiomyopathy (HCM).
Clear symbols indicate absence of evidence of HCM; solid symbols, clinically confirmed HCM; and symbols with slash, died of non‐HCM disease. Subject ages are in parentheses. Arrows indicate probands.
See this image and copyright information in PMC

References

    1. Maron BJ. Clinical course and management of hypertrophic cardiomyopathy. N Engl J Med. 2018;379:655–666. doi: 10.1056/NEJMra1710575 - DOI - PubMed
    1. Chou C, Chin MT. Pathogenic mechanisms of hypertrophic cardiomyopathy beyond sarcomere dysfunction. Int J Mol Sci. 2021;22:8933. doi: 10.3390/ijms22168933 - DOI - PMC - PubMed
    1. Braunwald E, Lambrew CT, Rockoff SD, Ross J Jr, Morrow AG. Idiopathic hypertrophic subaortic stenosis. I. A description of the disease based upon an analysis of 64 patients. Circulation. 1964;30:3–119. doi: 10.1161/01.cir.29.5s4.iv-3 - DOI - PubMed
    1. Ingles J, Burns C, Bagnall RD, Lam L, Yeates L, Sarina T, Puranik R, Briffa T, Atherton JJ, Driscoll T, et al. Nonfamilial hypertrophic cardiomyopathy: prevalence, natural history, and clinical implications. Circ Cardiovasc Genet. 2017;10:e001620. doi: 10.1161/CIRCGENETICS.116.001620 - DOI - PubMed
    1. Maron BA, Wang RS, Carnethon MR, Rowin EJ, Loscalzo J, Maron BJ, Maron MS. What causes hypertrophic cardiomyopathy? Am J Cardiol. 2022;179:74–82. doi: 10.1016/j.amjcard.2022.06.017 - DOI - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources