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Comment
. 2023 Dec;65(12):1544-1545.
doi: 10.1111/dmcn.15671. Epub 2023 Jun 11.

Succinic semialdehyde dehydrogenase deficiency: A model of neurocircuit imbalances in autism and potential insight into new biomarkers

Richard E Frye  1
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Succinic semialdehyde dehydrogenase deficiency: A model of neurocircuit imbalances in autism and potential insight into new biomarkers

Richard E Frye. Dev Med Child Neurol. 2023 Dec.
Free article
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References

REFERENCES

    1. Maenner MJ, Warren Z, Williams AR, et al. Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2020. MMWR Surveill Summ 2023; 72: 1-14.
    1. Jensen AR, Lane AL, Werner BA, et al. Modern Biomarkers for Autism Spectrum Disorder: Future Directions. Mol Diagn Ther 2022; 26: 483-95.
    1. Frye RE, Casanova MF, Fatemi SH, et al. Neuropathological Mechanisms of Seizures in Autism Spectrum Disorder. Front Neurosci 2016; 10: 192.
    1. Latzer IT, Hanson E, Bertoldi M, et al. Autism spectrum disorder and GABA levels in children with succinic semihaldehyde dehydrogenase deficiency. Dev Med Child Neurol 2023; 65: 1596-606.
    1. Zhang P, Omanska A, Ander BP, et al. Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex. Proc Natl Acad Sci U S A 2023; 120: e2206758120.

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