Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Aug;87(2):163-165.
doi: 10.1016/j.jinf.2023.06.002. Epub 2023 Jun 10.

Determinants of reinfection with SARS-CoV-2 Omicron variant

Affiliations
Comment

Determinants of reinfection with SARS-CoV-2 Omicron variant

N Bisharat et al. J Infect. 2023 Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Reinfection per day per 10,000 patients (daily incidence rate) during the Omicron surge based on age, vaccination status, and health status. On the X axis time period, from 01.12.2021 (an arbitrary date shortly before the begging of the Omicron surge) to the end of the study period (30.3.2022). Different color shades represent people younger than 50 years and older than 50 years. Reinfection incidence rates for non-vaccinated (NV) are shown in (a), for vaccinated before index infection (VBI) are shown in (b), (c), (d), and for vaccinated after index infection (VAI) are shown in (e) and (f).
Fig. 2
Fig. 2
Multivariate analysis of hazard ratios for reinfection based on vaccination status and time from last vaccination or infection. Cox model results for four independent factors: age (<50 yrs. vs.>50 yrs.), comorbidities (healthy vs. > 1 comorbidities), vaccination status (NV; never vaccinated, VBI vaccinated before index infection, VAI; vaccinated after index infection), and time from last vaccination or infection. Two sets are shown;> 50 years of age with comorbidities and< 50 years without comorbidities.

Comment on

References

    1. Camacho J., Zulaica J., Gimenez E., Rusu L., Velandia-Alvarez S., Albert E., et al. Neutralizing antibodies against Omicron BA.4/5 after COVID-19 vaccination in SARS-CoV-2 experienced versus naive individuals in the general population. J Infect. 2023;86(3):256–308. doi: 10.1016/j.jinf.2022.12.029. - DOI - PMC - PubMed
    1. Bobrovitz N., Ware H., Ma X., Li Z., Hosseini R., Cao C., et al. Protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the omicron variant and severe disease: a systematic review and meta-regression. Lancet Infect Dis. 2023;23(5):556–567. doi: 10.1016/S1473-3099(22)00801-5. - DOI - PMC - PubMed
    1. Ellingson K.D., Hollister J., Porter C.J., Khan S.M., Feldstein L.R., Naleway A.L., et al. Risk factors for reinfection with SARS-CoV-2 omicron variant among previously infected frontline workers. Emerg Infect Dis. 2023;29(3):599–604. doi: 10.3201/eid2903.221314. - DOI - PMC - PubMed
    1. Goldberg Y., Mandel M., Bar-On Y.M., Bodenheimer O., Freedman L.S., Ash N., et al. Protection and waning of natural and hybrid immunity to SARS-CoV-2. N Engl J Med. 2022;386(23):2201–2212. doi: 10.1056/NEJMoa2118946. - DOI - PMC - PubMed

Supplementary concepts