Cholinergic Nucleus 4 Degeneration in Isolated Rapid Eye Movement Sleep Behavior Disorder: One Piece of the Puzzle

Shady Rahayel^{1

2}, Ronald B Postuma^{2

3}, Jean-François Gagnon^{2

4}

Affiliations

¹ The Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Quebec, Canada.
² Centre for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada.
³ Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada.
⁴ Department of Psychology, University of Quebec in Montreal, Montreal, Quebec, Canada.

Comment

Shady Rahayel et al. Mov Disord. 2023 May.

. 2023 May;38(5):913-914.

doi: 10.1002/mds.29400.

Shady Rahayel^{1

2}, Ronald B Postuma^{2

3}, Jean-François Gagnon^{2

4}

¹ The Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Quebec, Canada.
² Centre for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada.
³ Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada.
⁴ Department of Psychology, University of Quebec in Montreal, Montreal, Quebec, Canada.

No abstract available

Comment on

Cholinergic Nucleus 4 Degeneration and Cognitive Impairment in Isolated Rapid Eye Movement Sleep Behavior Disorder.
Tan C, Nawaz H, Lageman SK, Cloud LJ, Amara AW, Newman BT, Druzgal TJ, Berman BD, Mukhopadhyay N, Barrett MJ. Tan C, et al. Mov Disord. 2023 Mar;38(3):474-479. doi: 10.1002/mds.29306. Epub 2023 Jan 4. Mov Disord. 2023. PMID: 36598142 Free PMC article.

1. Tan C, Nawaz H, Lageman SK, et al. Cholinergic nucleus 4 degeneration and cognitive impairment in isolated rapid eye movement sleep behavior disorder. Mov Disord 2023;38(3):474-479. https://doi.org/10.1002/mds.29306
1. Rémillard-Pelchat D, Rahayel S, Gaubert M, et al. Comprehensive analysis of brain volume in REM sleep behavior disorder with mild cognitive impairment. J Parkinsons Dis 2022;12(1):229-241. https://doi.org/10.3233/JPD-212691
1. Miglis MG, Adler CH, Antelmi E, et al. Biomarkers of conversion to alpha-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder. Lancet Neurol 2021;20(8):671-684. https://doi.org/10.1016/S1474-4422(21)00176-9
1. Rahayel S, Postuma RB, Montplaisir J, et al. Cortical and subcortical gray matter bases of cognitive deficits in REM sleep behavior disorder. Neurology 2018;90(20):e1759-e1770. https://doi.org/10.1212/WNL.0000000000005523
1. Hanyu H, Inoue Y, Sakurai H, et al. Voxel-based magnetic resonance imaging study of structural brain changes in patients with idiopathic REM sleep behavior disorder. Parkinsonism Relat Disord 2012;18(2):136-139. https://doi.org/10.1016/j.parkreldis.2011.08.023