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Review
. 2023 Jun;14(3):161-166.
doi: 10.14740/cr1490. Epub 2023 May 26.

Ultrasound-Accelerated Catheter-Directed Thrombolysis

Mrhaf Alsamman  1   2 , Ali Mohsin Choudhry  1   2 , Abdulaziz Mheir AlSaadi  1   2 , Rakesh Prashad  1   2
Affiliations
Review

Ultrasound-Accelerated Catheter-Directed Thrombolysis

Mrhaf Alsamman et al. Cardiol Res. 2023 Jun.

Abstract

Venous thromboembolism is a very common presentation in the hospital setting. In patients with high-risk pulmonary embolism (PE) or PE and hemodynamic instability, systemic thrombolytic treatment is generally indicated. In those with contraindications to systemic thrombolysis, catheter-directed local thrombolytic therapy and surgical embolectomy are currently considered. In particular, catheter-directed thrombolysis (CDT) is a drug delivery system coupling the endovascular drug administration nearby in the thrombus and the local facilitating effect of ultrasounds. The applications of CDT are currently debated. Here we provide a systematic review of the clinical utilization of CDT.

Keywords: Catheter-directed thrombolysis; Deep venous thrombosis; Embolectomy; Pulmonary embolism; Venous thromboembolism.

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Conflict of interest statement

The authors affirm that they have no conflict of interest.

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