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Editorial
. 2023 Aug 1;44(29):2710-2712.
doi: 10.1093/eurheartj/ehad326.

A Grim link: the association between subclinical atherosclerosis and epigenetic age

Nivedhitha Velayutham  1 , Richard T Lee  1   2
Affiliations
Editorial

A Grim link: the association between subclinical atherosclerosis and epigenetic age

Nivedhitha Velayutham et al. Eur Heart J. .

Abstract

A potential mediatory role for systemic inflammation in the association between subclinical atherosclerosis and Grim epigenetic age acceleration, identified by multi-omics analyses utilizing participants in the Progression of Early Subclinical Atherosclerosis (PESA) study.

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Conflict of interest statement

Conflict of interest N.V. declares that she has no conflicts of interest. R.T.L. is a co-founder, scientific advisory board member, and private equity holder of Elevian, Inc., a member of the scientific advisory board of Revidia Therapeutics, Inc., and a consultant to BlueRock Therapeutics. The Lee laboratory has received funding support from Elevian, Inc. and BlueRock Therapeutics.

Figures

Graphical Abstract
Graphical Abstract
A potential mediatory role for systemic inflammation in the association between subclinical atherosclerosis and Grim epigenetic age acceleration, identified by multi-omics analyses utilizing participants in the Progression of Early Subclinical Atherosclerosis (PESA) study.
See this image and copyright information in PMC

Comment on

  • Subclinical atherosclerosis and accelerated epigenetic age mediated by inflammation: a multi-omics study.
    Sánchez-Cabo F, Fuster V, Silla-Castro JC, González G, Lorenzo-Vivas E, Alvarez R, Callejas S, Benguría A, Gil E, Núñez E, Oliva B, Mendiguren JM, Cortes-Canteli M, Bueno H, Andrés V, Ordovás JM, Fernández-Friera L, Quesada AJ, Garcia JM, Rossello X, Vázquez J, Dopazo A, Fernández-Ortiz A, Ibáñez B, Fuster JJ, Lara-Pezzi E. Sánchez-Cabo F, et al. Eur Heart J. 2023 Aug 1;44(29):2698-2709. doi: 10.1093/eurheartj/ehad361. Eur Heart J. 2023. PMID: 37339167 Free PMC article.

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