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. 2023 May;14(4):332-335.
doi: 10.6004/jadpro.2023.14.4.8. Epub 2023 May 1.

Heart Failure in a Patient With Metastatic Well-Differentiated Neuroendocrine Tumor

Amy Henderson  1 , Salwan Al Mutar  2
Affiliations

Heart Failure in a Patient With Metastatic Well-Differentiated Neuroendocrine Tumor

Amy Henderson et al. J Adv Pract Oncol. 2023 May.

Abstract

Patients with neuroendocrine malignancy with liver metastases are at risk for carcinoid heart disease which, if left unchecked, can lead to heart failure. This case study demonstrates a clinical situation in which an advanced practitioner performed a thorough workup consisting of lab work and imaging studies, including echocardiogram, cardiac MRI, and dotatate PET/CT, as well as outside record review and comprehensive physical exam. Early detection, intervention, and control of disease are paramount to prevent potentially life-limiting carcinoid heart disease.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Ga-68 dotatate PET/CT scan demonstrating innumerable FDG-avid masses of the liver, consistent with Mrs. R's known history of metastatic neuroendocrine malignancy.
Figure 2
Figure 2
This illustration is consistent with carcinoid heart disease. Note the metastatic tumors in the liver, endocardial plaques within the right ventricle, and thickening of tricuspid and pulmonary valves (Mayo Clinic, 2015). Used with permission from the Mayo Foundation for Medical Education and Research. All rights reserved.
See this image and copyright information in PMC

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