Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jul-Aug;40(4):647-650.
doi: 10.1111/pde.15363. Epub 2023 Jun 14.

Clinical and epidemiological risk factors for infantile hemangioma: A case-control study

Ahmed Samaouel Chehad  1 , Odai Hamza  1 , Tarek Mansoul  1
Affiliations

Clinical and epidemiological risk factors for infantile hemangioma: A case-control study

Ahmed Samaouel Chehad et al. Pediatr Dermatol. 2023 Jul-Aug.

Abstract

There is limited data on risk-factors of infantile hemangioma (IH) in African and Arab countries. One hundred thirty-two patients with IH were enrolled and compared to 282 healthy controls. Female sex (odds ratios [OR]: 2.2; 95% confidence interval [CI] 1.4-3.6), low birth weight (OR: 4.5; 95% CI 1.9-10.6), and progesterone intake (OR: 38.6; 95% CI 5-296) were the only independent risk factors identified for development of IH, while no associations were found multiple gestation and preeclampsia.

Keywords: benign neoplasm; hemangioma; infant; risk factors; tumor.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

REFERENCES

    1. Smith CJF, Friedlander SF, Guma M, Kavanaugh A, Chambers CD. Infantile hemangiomas: an updated review on risk factors, pathogenesis, and treatment. Birth Defects Res. 2017;109(11):809-815. doi:10.1002/bdr2.1023
    1. Ding Y, Zhang JZ, Yu SR, Xiang F, Kang XJ. Risk factors for infantile hemangioma: a meta-analysis. World J Pediatr. 2020;16(4):377-384. doi:10.1007/s12519-019-00327-2
    1. Drolet BA, Swanson EA, Frieden IJ, Hemangioma Investigator Group. Infantile hemangiomas: an emerging health issue linked to an increased rate of low birth weight infants. J Pediatr. 2008;153(5):712-715.e1. doi:10.1016/j.jpeds.2008.05.043
    1. Li J, Chen X, Zhao S, et al. Demographic and clinical characteristics and risk factors for infantile hemangioma: a Chinese case-control study. Arch Dermatol. 2011;147(9):1049-1056. doi:10.1001/archdermatol.2011.122
    1. Hoornweg MJ, Smeulders MJ, Ubbink DT, van der Horst CM. The prevalence and risk factors of infantile haemangiomas: a case-control study in the Dutch population. Paediatr Perinat Epidemiol. 2012;26(2):156-162. doi:10.1111/j.1365-3016.2011.01214.x

LinkOut - more resources