Is movement variability altered in people with chronic non-specific low back pain? A systematic review

Abstract

Background: Variability in spine kinematics is a common motor adaptation to pain, which has been measured in various ways. However, it remains unclear whether low back pain (LBP) is typically characterised by increased, decreased or unchanged kinematic variability. Therefore, the aim of this review was to synthesise the evidence on whether the amount and structure of spine kinematic variability is altered in people with chronic non-specific LBP (CNSLBP).

Methods: Electronic databases, grey literature, and key journals were searched from inception up to August 2022, following a published and registered protocol. Eligible studies must investigated kinematic variability in CNSLBP people (adults ≥18 years) while preforming repetitive functional tasks. Two reviewers conducted screening, data extraction, and quality assessment independently. Data synthesis was conducted per task type and individual results were presented quantitatively to provide a narrative synthesis. The overall strength of evidence was rated using the Grading of Recommendations, Assessment, Development and Evaluation guidelines.

Findings: Fourteen observational studies were included in this review. To facilitate the interpretation of the results, the included studies were grouped into four categories according to the task preformed (i.e., repeated flexion and extension, lifting, gait, and sit to stand to sit task). The overall quality of evidence was rated as a very low, primarily due to the inclusion criteria that limited the review to observational studies. In addition, the use of heterogeneous metrics for analysis and varying effect sizes contributed to the downgrade of evidence to a very low level.

Interpretation: Individuals with chronic non-specific LBP exhibited altered motor adaptability, as evidenced by differences in kinematic movement variability during the performance of various repetitive functional tasks. However, the direction of the changes in movement variability was not consistent across studies.

Fig 1. Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 flow diagram.

*Other resources that were identified through searching the gray literature and hand search.

Fig 2. Differences in movement variability between people with LBP and healthy controls (CON) while preforming repeated flexion and extension tasks.

Abbreviations: Sym: symmetric; Asym: Asymmetric; %DET: Percentage determinism; SaEn: Sample entropy; Var: Variability.

Fig 3. Differences in movement variability between people with LBP and healthy controls (CON) while preforming lifting tasks.

Abbreviations: DET: Determinism; REC: recurrence rate; Var: Variability.

Fig 4. Differences in movement variability between people with LBP and healthy controls (CON) during walking or running tasks.

Abbreviations: CV: Coefficient of Variation; SD: Standard deviation: Var: Variability.

Fig 5. Differences in movement variability between people with LBP and healthy controls (CON) during sit to stand task.

Abbreviations: SD: Standard deviation: Var: Variability.