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Comment
. 2023 Jun 13;56(6):1157-1159.
doi: 10.1016/j.immuni.2023.05.012.

Older and wiser: The benefits to neonates of aged neutrophils

George B Collins  1 , Derek Gilroy  2
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Older and wiser: The benefits to neonates of aged neutrophils

George B Collins et al. Immunity. .
Free article

Abstract

Neonates are relatively protected from non-neonatal pathogens by unclear mechanisms. In this issue of Immunity, Bee et al.1 show that resistance to Streptococcus pneumoniae in neonatal mice is mediated by dampened neutrophil efferocytosis, accumulation of aged neutrophils, and enhanced CD11b-dependent bacterial opsonophagocytosis.

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