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Review
. 2023 Jul;83(11):1039-1043.
doi: 10.1007/s40265-023-01904-6.

Tofersen: First Approval

Hannah A Blair  1
Affiliations
Review

Tofersen: First Approval

Hannah A Blair. Drugs. 2023 Jul.

Abstract

Tofersen (Qalsody™) is an antisense oligonucleotide being developed by Biogen for the treatment of amyotrophic lateral sclerosis (ALS). On 25 April 2023, tofersen was approved in the USA for the treatment of ALS in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene. This article summarizes the milestones in the development of tofersen leading to this first approval for ALS.

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References

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