Visual evoked cortical potential to paracentral retinal stimulation in chronic glaucoma, ocular hypertension, and an age-matched group of normals

Abstract

Visual evoked cortical potentials (VECPs) to midperipheral stimulation of the visual field were elicited in age-matched groups of patients with unilateral chronic simple glaucoma or ocular hypertension and normal subjects. With a multimodal stimulus approach comprising transient and steady-state pattern reversal and transient onset-offset VECPs, 82.1% of the glaucoma group and 50.9% of the ocular hypertensives revealed significant abnormalities (p less than 0.01) in one or more of the electrophysiological features measured, i.e., latency, phase, amplitude, and contrast threshold.