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. 1986:31 Suppl 3:7-10.
doi: 10.2165/00003495-198600313-00004.

Serological identification of Branhamella catarrhalis. Serological evidence for infection

I Eliasson

Serological identification of Branhamella catarrhalis. Serological evidence for infection

I Eliasson. Drugs. 1986.

Abstract

A protein antigen--P-antigen--characteristic of Branhamella catarrhalis has been described. Precipitating antibodies against this antigen occur in a majority of healthy human sera; serological evidence for a pathogenic role of B. catarrhalis is accumulating. The occurrence of complement-fixing antibodies has been demonstrated during bronchopulmonary infection with B. catarrhalis and in maxillary sinusitis. Increases in antibody titres assessed by an enzyme-linked immunosorbent assay (ELISA) technique have been reported in children with acute otitis media. An ELISA, using purified P-antigen, for the evaluation of IgG, IgM and IgA antibodies against B. catarrhalis is being developed.

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