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Review
. 2022 Nov-Dec;13(6):745-754.
doi: 10.32598/bcn.2021.2168.2. Epub 2022 Nov 1.

Complete Blood Count Parameters as Prognostic Factor of Stroke: A Systematic Review

Samad Shams Vahdati  1 , Alireza Ala  1 , Nafiseh Vahed  2 , Sahar Mohammadi  3 , Hoorolnesa Ameli  4
Affiliations
Review

Complete Blood Count Parameters as Prognostic Factor of Stroke: A Systematic Review

Samad Shams Vahdati et al. Basic Clin Neurosci. 2022 Nov-Dec.

Abstract

Introduction: Stroke is known as a common cause of disability all over the world. Stroke prognosis estimation has always been a topic of interest. In this study, it was tried to investigate the prognostic value of laboratory findings of complete blood count in a systematic review.

Methods: In this systematic review, literature from Medline via (PubMed, Ovid) Embase, Scopus, Cochrane Library, and ProQuest between 1988 and 2020 were included. A combination of Mesh and free terms were included in the search strategy: "Stroke", "Red Cell Distribution Width", "Blood Cell Count", "Mean corpuscular hemoglobin", and "Mean Corpuscular Volume" and with the abbreviation, in all fields. Data synthesis was achieved using content analysis.

Results: Elevated red blood cell distribution width was associated with stroke, cardiovascular events, and all-cause deaths among patients with prior stroke. Mean platelet volume has not any prognostic significance in ischemic stroke. There was a poor association between mean corpuscular volume (MCV) and stroke prognosis. Globulin and hemoglobin level predicted short-term mortality following acute ischemic stroke.

Conclusion: Complete blood count as a routine and efficient test performed in health care centers can be used to estimate the prognosis of stroke.

Keywords: Blood cell count; Erythrocyte indices; Prognosis; Stroke.

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Conflict of interest statement

Conflict of interest The Authors declare no conflict of interest.

Figures

Figure 1.
Figure 1.
Search and selection process of the systematic review. Polymorph, mononuclear cells, total protein level, and other CBC parameters were reported and surveyed in the studies.
See this image and copyright information in PMC

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