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Review
. 2023 Jun;9(3):153-159.
doi: 10.1159/000528122. Epub 2023 Mar 23.

Hidradenitis Suppurativa and Five Key Vitamins and Minerals

Sydney Alexis Weir  1 , Brittany Roman  1 , Victoria Jiminez  1 , Meredith Burns  1 , Adaugo Sanyi  2 , Boni Elewski  2 , Tiffany Mayo  2
Affiliations
Review

Hidradenitis Suppurativa and Five Key Vitamins and Minerals

Sydney Alexis Weir et al. Skin Appendage Disord. 2023 Jun.

Abstract

Hidradenitis suppurativa (HS), a chronic inflammatory disease characterized by painful abscesses and nodules, has limited effective treatment options. However, adjuncts to standard therapeutics such as dietary modifications have been increasingly investigated in recent years. This comprehensive review aimed to analyze the literature concerning the relationship between HS and 28 essential vitamins and minerals. A literature search was performed via PubMed, Embase, Ovid, and Scopus using search terms related to HS and the essential vitamins and minerals. A total of 215 unique articles were identified and analyzed. Twelve essential nutrients had documented associations with HS; definitive supplementation or monitoring recommendations were identified for 7 of the 12 HS-associated nutrients in the literature. Evidence is growing that supports adjunct supplementation of zinc, vitamin A, and vitamin D in the treatment of HS. Further, obtaining serum levels of zinc, vitamin A, vitamin D, and vitamin B12 upon initial diagnosis of HS may be beneficial to optimize standard HS treatment. In conclusion, optimizing nutrition in addition to standard HS therapeutics may help reduce disease burden; however more research is needed.

Keywords: Hidradenitis suppurativa; Minerals; Nutrition; Supplements; Vitamins.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1
Fig. 1
Illustration of literature review study design.
See this image and copyright information in PMC

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