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Comment
. 2023 Jun 15;83(12):1961-1963.
doi: 10.1016/j.molcel.2023.05.024.

Stressing the role of a short linear motif in ataxin-2 condensation

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Stressing the role of a short linear motif in ataxin-2 condensation

Tom Scheidt et al. Mol Cell. .
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Abstract

Ataxin-2, an RNA-binding protein that is conserved across eukaryotes, is involved in stress granule assembly and age-associated neurodegenerative diseases. In this issue of Molecular Cell, Boeynaems et al.1 identify a short linear motif in ataxin-2 as a condensation switch, providing molecular insights into its essential role in cellular stress response.

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Declaration of interests The authors declare no competing interests.

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