Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2023 Oct;39(7):e3677.
doi: 10.1002/dmrr.3677. Epub 2023 Jun 17.

The effect of home-based resistance exercise training in people with type 2 diabetes: A randomized controlled trial

Ebaa Al Ozairi  1   2 , Dalal Alsaeed  1 , Dherar Al Roudhan  1 , Mohammed Jalali  1 , Anant Mashankar  1 , Dennis Taliping  1 , Amal Abdulla  1 , Jason M R Gill  3 , Naveed Sattar  3 , Paul Welsh  3 , Stuart R Gray  3
Affiliations
Free article
Randomized Controlled Trial

The effect of home-based resistance exercise training in people with type 2 diabetes: A randomized controlled trial

Ebaa Al Ozairi et al. Diabetes Metab Res Rev. 2023 Oct.
Free article

Abstract

Aims: To evaluate the effects of pragmatic home-based resistance exercise training on glycated haemoglobin (HbA1c) as well as muscle strength and body composition in people with type 2 diabetes.

Materials and methods: People with type 2 diabetes were randomized (1:1) to usual care or usual care plus home-based resistance exercise for 32 weeks. The changes in HbA1c, body composition, physical function, quality of life, continuous glucose monitoring and liver fat were compared by randomized group using linear regression.

Results: This study recruited 120 participants (female: n = 46 [38%], age 60.2 (9.4) years, BMI 31.1 (5.4) kg.m-2 ), 64 to intervention and 56 to usual care. Intention to treat analysis revealed no effect on HbA1c (difference in difference: -0.4 mmol/mol, 95% confidence interval [CI]: -3.26, 2.47; p = 0.78) but the intervention increased the number of push-ups (3.6 push-ups, 95% CI: 0.8, 6.4), arm lean mass (116 g, 95% CI: 6, 227) and leg lean mass (438 g, 95% CI 65, 810) and decreased liver fat (-1.27%, 95% CI -2.17, -0.38), with no differences in other outcomes. Per-protocol analysis revealed similar results.

Conclusions: Home-based resistance exercise is unlikely to lower HbA1c in people with type 2 diabetes but may be of benefit for maintaining muscle mass and function and reducing liver fat.

Keywords: body composition; glycaemic control; muscle; resistance exercise; strength; type 2 diabetes.

PubMed Disclaimer

References

REFERENCES

    1. International Diabetes Federation. Diabetes Atlas; 2021.
    1. Klein R, Klein BEK, Moss SE. Relation of glycemic control to diabetic microvascular complications in diabetes mellitus. Ann Intern Med. 1996;124(1_Part_2):90-96. https://doi.org/10.7326/0003-4819-124-1_Part_2-199601011-00003
    1. Fowler MJ. Microvascular and macrovascular complications of diabetes. Clin Diabetes. 2008;26(2):77-82. LP - 82. https://doi.org/10.2337/diaclin.26.2.77
    1. Morrish NJ, Wang SL, Stevens LK, Fuller JH, Keen H. Mortality and causes of death in the WHO multinational study of vascular disease in diabetes. Diabetologia. 2001;44((Suppl 2)):S14-S21. https://doi.org/10.1007/pl00002934
    1. Pan B, Ge L, qin XY, et al. Exercise training modalities in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis. Int J Behav Nutr Phys Activ. 2018;15(1):1-14. https://doi.org/10.1186/s12966-018-0703-3

Publication types