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Multicenter Study
. 2023 Sep;89(3):143-152.
doi: 10.1111/cod.14357. Epub 2023 Jun 18.

Hand eczema in glove-wearing patients

Aude Clément  1 , Marie-Christine Ferrier le Bouëdec  1 , Marie-Noëlle Crépy  2 , Nadia Raison-Peyron  3 , Florence Tétart  4 , Pierre Marcant  5 , Pauline Pralong  6 , Aude Valois  7 , Justine Pasteur  1 , Haudrey Assier  8 , Claire Bernier  9 , Marie-Thérèse Le Cam  10 , Florence Hacard  11 , Audrey Nosbaum  11 , Françoise Giordano Labadie  12 , Cécile Morice  13 , Camille Leleu  14 , Brigitte Milpied  15 , Anne-Sophie Darrigade  15 , Juliette Delaunay  16 , Annick Barbaud  17 , Florence Castelain  18 , Evelyne Collet  14 , Emmanuelle Amsler  17 ; from the Dermatology and Allergology group of the French Society of Dermatology (DAG)
Affiliations
Multicenter Study

Hand eczema in glove-wearing patients

Aude Clément et al. Contact Dermatitis. 2023 Sep.

Abstract

Background: Allergic contact dermatitis to gloves is mostly induced by rubber accelerators. The European baseline series (EBS) appears insufficient to detect glove allergy. Since 2017, it is recommended to use the European rubber series (ERS) and to test the patients' own gloves.

Objectives: To investigate the clinical profile of glove-wearing patients with hand eczema (HE) and to evaluate their sensitisation profile to glove allergens and the value of testing the patients' own gloves.

Methods: We conducted a French multicentre study of patients evaluated for HE between 2018 and 2020 and tested with the EBS, the ERS and their own gloves in patch tests and semi-open (SO) tests.

Results: A total of 279 patients were included; 32.6% of patients had positive tests to their own gloves or to glove allergens. Almost 45% of the sensitisations to glove allergens were detected only by the ERS. Among the patients tested both in patch tests and SO tests with their own gloves with positive results, 28% had positive SO tests only. Polyvinylchloride (PVC) gloves were positive in four patients.

Conclusion: Our series confirms the need to test the ERS. All the patients' gloves must also be tested including PVC gloves. SO tests with gloves are useful as a complement to patch tests.

Keywords: contact dermatitis; gloves; hand eczema; patch test; rubber; semi-open test.

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References

REFERENCES

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