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. 2023 Jul:117:103994.
doi: 10.1016/j.medengphy.2023.103994. Epub 2023 May 17.

Impact of lock solutions on the mechanical performance of polyurethane central venous catheters: A comparative study

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Impact of lock solutions on the mechanical performance of polyurethane central venous catheters: A comparative study

Afif Khzam et al. Med Eng Phys. 2023 Jul.

Abstract

The impact of ethanol locks on the mechanical performances of central venous catheters was compared to that of aqueous-based locks. Several mechanical tests were performed to evaluate catheter behavior: kinking radius measurements, burst pressure, and tensile tests. Different polyurethanes were studied to assess the impact of radio-opaque charge and polymer chemical composition on catheter behavior. The results were correlated to swelling measurements and calorimetric measurements. In particular, ethanol locks have a higher impact on long contact time than aqueous-based locks: stresses and strains at break were lower, and kinking radii were higher. However, for all catheters, the mechanical performances remain much higher than the normative requirements.

Keywords: Burst pressure; Central venous catheter; Ethanol lock; Kinking; Polyurethane; Tensile testing.

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Conflict of interest statement

Declaration of Competing Interest there was a partnership with Vygon company concerning A. Khzam‘s doctoral fellowship.

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