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Case Reports
. 2023 Jun 15;2023(6):rjad310.
doi: 10.1093/jscr/rjad310. eCollection 2023 Jun.

OK432 sclerotherapy for refractory chylous leakage after neck dissection

Yuiko Hashimoto  1 , Masanori Teshima  1 , Mitsuko Yui  1 , Shun Tatehara  1 , Keisuke Iritani  1 , Tatsuya Furukawa  1 , Hirotaka Shinomiya  1 , Ken-Ichi Nibu  1
Affiliations
Case Reports

OK432 sclerotherapy for refractory chylous leakage after neck dissection

Yuiko Hashimoto et al. J Surg Case Rep. .

Abstract

Chylous leakage is a rare but serious postoperative complication of neck dissection (ND). Most chylous leakages are successfully treated either by drainage or ligation of the thoracic duct, but the resolution is occasionally prolonged. OK432 sclerotherapy is used to treat various refractory cystic diseases of the head and neck. Three patients were treated with OK432 sclerotherapy for refractory chylous leakage following ND. Case 1 involved a 77-year-old man with chylous leakage after a total laryngectomy and bilateral ND. Case 2 involved a 71-year-old woman who underwent total thyroidectomy and left ND for thyroid cancer. Case 3 involved a 61-year-old woman who underwent right ND for oropharyngeal cancer. In all patients, chylous leakage rapidly improved after OK432 injection without any complications. Our results suggest the efficacy of OK432 sclerotherapy in patients with refractory chylous leakage after ND.

Keywords: chylous leakage; complication; head and neck cancer; intractable; neck dissection.

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Conflict of interest statement

None declared.

Figures

Figure 1
Figure 1
Enhanced CT before and after OK432 injection. (A) Before OK432 injection. Cervical CT shows a chylous leakage in the left supraclavicular fossa. (B) After two cycles of OK4432 injection. The chylous leakage completely disappeared after OK432 sclerotherapy.
Figure 2
Figure 2
Enhanced CT before and after OK432 injection. (A) Before OK432 injection. The lymph (dashed circle) is retained in the right supraclavicular fossa. (B) After injection. The lymphatic leakage disappeared after OK432 sclerotherapy.
See this image and copyright information in PMC

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