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. 2023 Jun 2:5:1196125.
doi: 10.3389/fmedt.2023.1196125. eCollection 2023.

Effects of helical centerline stent vs. straight stent placement on blood flow velocity

Yutaro Kohata  1   2 , Makoto Ohta  2   3 , Kazuyoshi Jin  1   2 , Hitomi Anzai  2
Affiliations

Effects of helical centerline stent vs. straight stent placement on blood flow velocity

Yutaro Kohata et al. Front Med Technol. .

Abstract

As an approach to maintain patency in femoropopliteal stenting, a helical stent configuration was proposed, which showed improved patency in clinical trials. However, the effects of helical stent placement on the flow have not been quantitatively analyzed. The purpose of this study was to estimate flow velocities to quantify the influence of helical stent placement. Helical and straight stents were implanted in three healthy pigs, and the flow velocities were estimated using the time-intensity curve (TIC) in the angiography images. The angiographic images indicated thinning of the leading edge of the contrast medium through the helically deformed artery, which was not observed in the straight stent. The slower rise of the TIC peak in the helical stent indicated faster travel of this thinner edge. Arterial expansion due to stenting was observed in all cases, and the expansion rate varied according to location. All cases of helical stent implantation showed that velocity was maintained (55.0%-71.3% velocity retention), unlike for straight stent implantation (43.0%-68.0% velocity retention); however, no significant difference was observed.

Keywords: angiography images; blood flow velocities; helical stent; swirling flow; time-intensity curve (TIC).

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Conflict of interest statement

This study was funded by Otsuka Medical Devices Co., Ltd. (Tokyo, Japan). The funder had the following involvement in the study: data collection for animal tests. The authors have no competing interests to declare.

Figures

Figure 1
Figure 1
Angiography images acquired (A) before and (B) after stent placement in Case 1. The red arrows indicate the right carotid artery in which a helical stent was placed. The blue arrows indicate the left carotid artery in which a straight stent was placed. Time-intensity curves (TICs) (C) before and (D) after helical stent placement for Case 1. The solid lines and dotted lines indicate TICs at a proximal and distal region of interest (ROI), respectively. The green arrows indicate the detected peaks in the TIC.
Figure 2
Figure 2
(A) Angiography image after stent placement in case 1. Helical deformation of the animal's right (helical-centerline stented) ICA, but not of the right (straight-centerline stented) ICA. (B) shows that leading edges of contrast appears thinner in helical-centerline stented ICA but not in the straight-centerline stented ICA.
See this image and copyright information in PMC

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