Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 May 4;23(3):196-198.
doi: 10.1177/15357597231164276. eCollection 2023 May-Jun.

Somatic Variants and Surgical Epilepsies: Search and You Will Find

Danielle M Andrade  1
Affiliations
Comment

Somatic Variants and Surgical Epilepsies: Search and You Will Find

Danielle M Andrade. Epilepsy Curr. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Comment on

  • Detection of brain somatic variation in epilepsy-associated developmental lesions.
    Bedrosian TA, Miller KE, Grischow OE, Schieffer KM, LaHaye S, Yoon H, Miller AR, Navarro J, Westfall J, Leraas K, Choi S, Williamson R, Fitch J, Kelly BJ, White P, Lee K, McGrath S, Cottrell CE, Magrini V, Leonard J, Pindrik J, Shaikhouni A, Boué DR, Thomas DL, Pierson CR, Wilson RK, Ostendorf AP, Mardis ER, Koboldt DC. Bedrosian TA, et al. Epilepsia. 2022 Aug;63(8):1981-1997. doi: 10.1111/epi.17323. Epub 2022 Jun 23. Epilepsia. 2022. PMID: 35687047

References

    1. Steinlein OK, Mulley JC, Propping P, et al.A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy. Nat Genet. 1995;11(2):201–203. doi:10.1038/ng1095-201 - PubMed
    1. Poduri A, Evrony GD, Cai X, et al.Somatic activation of AKT3 causes hemispheric developmental brain malformations. Neuron. 2012;74(1):41–48. doi:10.1016/j.neuron.2012.03.010 - PMC - PubMed
    1. Lee JH, Huynh M, Silhavy JL, et al.De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly. Nat Genet. 2012;44(8):941–945. doi:10.1038/ng.2329 - PMC - PubMed
    1. Rivera B, Gayden T, Carrot-Zhang J, et al.Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors. Acta Neuropathol. 2016;131(6):847–863. doi:10.1007/s00401-016-1549-x - PMC - PubMed
    1. Martinoni M, Marucci G, de Biase D, et al.BRAF V600E mutation in neocortical posterior temporal epileptogenic gangliogliomas. J Clin Neurosci. 2015;22(8):1250–1253. doi:10.1016/j.jocn.2015.02.016 - PubMed

LinkOut - more resources