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. 2023 Sep;10(9):5989-5998.
doi: 10.1002/nop2.1906. Epub 2023 Jun 19.

Effectiveness and methods of cryotherapy in reducing swelling after total knee arthroplasty: A systematic review on randomized controlled trials

Yoonyoung Lee  1 , Yong Soon Shin  2 , Hyun Jung Kim  3 , Jiwon An  4
Affiliations

Effectiveness and methods of cryotherapy in reducing swelling after total knee arthroplasty: A systematic review on randomized controlled trials

Yoonyoung Lee et al. Nurs Open. 2023 Sep.

Abstract

Aim: This study aims to investigate the effect and methods of cryotherapy in reducing swelling after total knee arthroplasty.

Design: Systematic review.

Methods: We searched PubMed, Embase, CINAHL, Cochrane Library, KoreaMed, KERIS and National Science Digital Library for randomized controlled trials on 19 August 2021. This systematic review was conducted according to the PRISMA 2009 checklist.

Results: A total of eight randomized controlled trials were systematically reviewed to determine the effect and methods of cryotherapy on reducing postoperative swelling. The effects were not significantly different in six studies. Application time per cryotherapy session was 10-20 min when using an ice pack and up to 48 h when using an automated device. The duration ranged from 2 days to 1 week or until discharge, and the frequency varied from 2 to 72 times per day.

Keywords: cryotherapy; evidence-based practice; intervention research; nursing practice; postoperative nursing; swelling; systematic reviews; total knee arthroplasty.

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Conflict of interest statement

The authors declare no conflict of interests.

Figures

FIGURE 1
FIGURE 1
PRISMA flow diagram.
FIGURE 2
FIGURE 2
Risk of bias result.
FIGURE 3
FIGURE 3
Risk of bias summary.
See this image and copyright information in PMC

References

    1. Abramson, D. I. , Chu, L. S. , Tuck, S., Jr. , Lee, S. W. , Richardson, G. , & Levin, M. (1966). Effect of tissue temperatures and blood flow on motor nerve conduction velocity. JAMA, 198(10), 1082–1088. - PubMed
    1. Adie, S. , Kwan, A. , Naylor, J. M. , Harris, I. A. , & Mittal, R. (2012). Cryotherapy following total knee replacement. Cochrane Database of Systematic Reviews, 12(9), Cd007911. 10.1002/14651858.CD007911.pub2 - DOI - PubMed
    1. Borgers, A. , Cuppens, K. , Janssen, P. , & Vanlommel, E. (2020). A prospective comparative study between a cooling device and manual cooling after total knee arthroplasty. Acta Orthopaedica Belgica, 86(2), 287–293. - PubMed
    1. Brouwers, H. , de Vries, A. J. , van Zuilen, M. , van Kouswijk, H. W. , & Brouwer, R. W. (2022). The role of computer‐assisted cryotherapy in the postoperative treatment after total knee arthroplasty: Positive effects on pain and opioid consumption. Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA, 30(8), 2698–2706. 10.1007/s00167-021-06568-x - DOI - PubMed
    1. Brown, W. C. , & Hahn, D. B. (2009). Frostbite of the feet after cryotherapy: A report of two cases. The Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons, 48(5), 577–580. 10.1053/j.jfas.2009.06.003 - DOI - PubMed

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