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. 2023 May 19;102(20):e33759.
doi: 10.1097/MD.0000000000033759.

An analysis of risk factors for clinically relevant pancreatic fistulas after laparoscopic pancreaticoduodenectomy

Guoli Chen  1 , Zhifang Zheng  2 , Haizhao Yi  1 , Qiuju Yue  1 , Lijie Li  1
Affiliations

An analysis of risk factors for clinically relevant pancreatic fistulas after laparoscopic pancreaticoduodenectomy

Guoli Chen et al. Medicine (Baltimore). .

Abstract

This study aimed to explore the risk factors of clinically relevant pancreatic fistulas (PF) after laparoscopic pancreaticoduodenectomy (LPD). The clinical data of 80 patients who underwent pancreaticoduodenectomy in our hospital were retrospectively analyzed. The potential risk factors for PF after LPD were determined using univariate and multivariate logistic regression analyses. Results from the univariate analyses showed that the pancreatic duct diameter (P < .001), pancreatic texture (P < .001), abdominal infection (P = .002), and reoperation (P < .001) were associated with clinically relevant PF. Results from the multivariate logistic regression analysis showed that the pancreatic duct diameter (P = .002) and pancreatic texture (P = .016) were significant risk factors for clinically relevant PF. Based on this study, the pancreatic duct diameter and pancreatic texture are independent risk factors for clinically relevant PF after LPD.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

References

    1. Kawaida H, Kono H, Hosomura N, et al. . Surgical techniques and postoperative management to prevent postoperative pancreatic fistula after pancreatic surgery. World J Gastroenterol. 2019;25:3722–37. - PMC - PubMed
    1. Zhang B, Yuan Q, Li S, et al. . Risk factors of clinically relevant postoperative pancreatic fistula after pancreaticoduodenectomy: a systematic review and meta-analysis. Medicine (Baltim). 2022;101:e29757. - PMC - PubMed
    1. Nemoto M, Koyama K, Enokido M, et al. . Stent graft treatment for ruptured pseudoaneurysms of the splanchnic arteries after pancreaticoduodenectomy: a case report. Surg Case Rep. 2020;6:122. - PMC - PubMed
    1. Takagi K, Umeda Y, Yoshida R, et al. . Surgical techniques of gastrojejunostomy in robotic pancreatoduodenectomy: robot-sewn versus stapled gastrojejunostomy anastomosis. J Clin Med. 2023;12:732. - PMC - PubMed
    1. Panni RZ, Guerra J, Hawkins WG, et al. . National pancreatic fistula rates after minimally invasive pancreaticoduodenectomy: a NSQIP analysis. J Am Coll Surg. 2019;229:192–199.e1. - PubMed

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