Retraction

Abstract

Retraction: Pavelka, K., Trč, T., Karpaš, K., Vítek, P., Sedláčková, M., Vlasáková, V., Böhmová, J. and Rovenský, J. (2007), The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: A randomized, multicenter, double-blind, placebo-controlled study with primary end points at two months after the end of a three-month treatment period. Arthritis & Rheumatism, 56: 4055-4064. https://doi.org/10.1002/art.23056. The above article, published online on November 29, 2007 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal's Editor-in-Chief, Dr. Daniel H. Solomon, the American College of Rheumatology, and Wiley Periodicals LLC. The retraction has been agreed following a post-hoc analysis by the research's funder, TRB Chemedica International SA, that identified a discrepancy between the preliminary results of the post-hoc analysis and the results of the published article. The statistical analysis performed using the original database is deemed no longer reliable and the conclusions of the original study regarding the efficacy of diacerein versus placebo are not supported by robust data. As a result, the editors and funder are issuing this retraction.