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. 2023 Jun 19:21:eAO0215.
doi: 10.31744/einstein_journal/2023AO0215. eCollection 2023.

Is physical inactivity and sedentary behavior associated with tumor stage in breast cancer patients? A cross-sectional study of Brazilian women

Luana de Lima Queiroga  1 , Rafael Mathias Pitta  1 , Mayra de França Trevisani  2 , Carla Giuliano de Sá Pinto Montenegro  1 , Diogo Diniz Gomes Bugano  1 , Aylton José Figueira Junior  2 , Julien Steven Baker  3 , Danilo Sales Bocalini  4 , Luciana Diniz Nagem Janot de Matos  1
Affiliations

Is physical inactivity and sedentary behavior associated with tumor stage in breast cancer patients? A cross-sectional study of Brazilian women

Luana de Lima Queiroga et al. Einstein (Sao Paulo). .

Abstract

Objective: A comparative analysis of the association between sedentary behavior versus physical activity levels and tumor staging in women with breast cancer.

Methods: The present research adopted a cross-sectional study design to recruit a total of 55 adult and elderly women newly diagnosed with breast cancer for data collection and analysis. Inclusion criteria involved patients in procession of a formal approval for participation in the study by the treating physician and those not hitherto subjected to the first cycle of chemotherapy.

Results: Physical activity levels did not influence the pathological stage of breast cancer (p=0.26) or histological tumor grade (p=0.07) in the analyzed subjects. However, there was a significant association between physical activity levels and responsiveness to hormones (epidermal growth factor receptor (HER2), p<0.05) in the analyzed subjects. Significant difference was detected in the histological tumor grade in relation to the mean time spent sitting during the weekend (p<0.05). However, sedentary behavior had no influence on the tumor stage (p>0.05).

Conclusion: Physical activity levels did not influence the tumor stage and histological tumor grade. Sedentary behavior had a significant influence on the histological tumor grade.

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Conflict of interest statement

Conflict of interest: none.

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