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Review
. 2023 Oct;22(4):437-448.
doi: 10.1007/s10689-023-00341-4. Epub 2023 Jun 21.

Cancer surveillance for transgender and gender diverse patients with Lynch syndrome: a practice resource of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer

Rachel Hodan #  1 , Linda Rodgers-Fouche #  2 , Anu Chittenden #  3 , Mev Dominguez-Valentin  4 , James Ferriss  5 , Lauren Gima  6 , Ole-Petter R Hamnvik  7 , Gregory E Idos  8 , Kevin Kline  9 , Diane R Koeller  3 , Jessica M Long  10 , Danielle McKenna  10 , Charles Muller  11 , Maxton Thoman  12 , Anton Wintner  12 , Bronwyn S Bedrick  13 ; Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
Affiliations
Review

Cancer surveillance for transgender and gender diverse patients with Lynch syndrome: a practice resource of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer

Rachel Hodan et al. Fam Cancer. 2023 Oct.

Abstract

Transgender and gender diverse (TGD) populations with hereditary cancer syndromes face unique obstacles to identifying and obtaining appropriate cancer surveillance and risk-reducing procedures. There is a lack of care provider knowledge about TGD health management. Lynch syndrome (LS) is one of the most common hereditary cancer syndromes, affecting an estimated 1 in 279 individuals. There are no clinical guidelines specific for TGD individuals with LS, highlighting a need to improve the quality of care for this population. There is an urgent need for cancer surveillance recommendations for TGD patients. This commentary provides recommendations for cancer surveillance, risk-reducing strategies, and genetic counseling considerations for TGD patients with LS.

Keywords: Cancer; Lynch syndrome; Management; Surveillance; Transgender and gender diverse.

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