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. 2023 Jul;29(7):1415-1419.
doi: 10.3201/eid2907.230216.

Pulmonary Nontuberculous Mycobacteria, Ontario, Canada, 2020

Theodore K Marras, Paul Nelson, Adriana Peci, Melissa Richard-Greenblatt, Sarah Brode, Ashleigh Sullivan, Frances B Jamieson, Julianne V Kus

Pulmonary Nontuberculous Mycobacteria, Ontario, Canada, 2020

Theodore K Marras et al. Emerg Infect Dis. 2023 Jul.

Abstract

We measured annual prevalence of microbiologically defined nontuberculous mycobacterial lung disease in Ontario, Canada. Mycobacterium avium prevalence was 13 cases/100,000 persons in 2020, a 2.5-fold increase from 2010, indicating a large increase in true M. avium lung disease. During the same period, M. xenopi decreased nearly 50%, to 0.84 cases/100,000 persons.

Keywords: Canada; Mycobacterium avium-intracellulare complex; Mycobacterium intracellulare; Ontario; atypical mycobacteria; bacteria; epidemiology; mycobacteria; nontuberculous mycobacteria; prevalence; pulmonary nontuberculous mycobacteria; respiratory infections; tuberculosis and other mycobacteria.

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Figures

Figure 1
Figure 1
Categories of nontuberculous mycobacteria pulmonary disease, Ontario, Canada, 2020. A) Uncertain state: 1 sputum culture. B) Standard microbiological criteria: >2 sputum cultures with the same species, or 1 bronchoscopic or lung biopsy culture. C) Strict microbiological criteria (subset of standard): >3 sputum cultures with the same species, or >2 bronchoscopic cultures with the same species, or 1 bronchoscopic plus 1 sputum culture with the same species, or 1 lung biopsy culture. Some images were obtained from Flaticon (https://www.flaticon.com).
Figure 2
Figure 2
Prevalence of nontuberculous mycobacterial pulmonary disease (standard definition) by Ontario health region, Ontario, Canada, 2020. Numbers below region names indicate number of cases per 100,000 population.
See this image and copyright information in PMC

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