Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun 23;11(1):34.
doi: 10.1186/s40635-023-00521-7.

Could daily changes in respiratory microbiota help predicting early Staphylococcus aureus ventilator-associated pneumonia?

Sylvain Meyer  1 , Nadia Gaïa  2 , Vladimir Lazarevic  2 , Jacques Schrenzel  2 , Bruno François  3   4   5 , Olivier Barraud  1   2   6 ; SCORPIUS study group
Collaborators, Affiliations

Could daily changes in respiratory microbiota help predicting early Staphylococcus aureus ventilator-associated pneumonia?

Sylvain Meyer et al. Intensive Care Med Exp. .
No abstract available

Keywords: Anaerobes; Respiratory microbiota; Staphylococcus aureus; Ventilator-associated pneumonia.

PubMed Disclaimer

Conflict of interest statement

All authors: nothing to declare.

Figures

Fig. 1
Fig. 1
Microbiota differences of early S. aureus VAP vs non-VAP patients during the first 3 days of intubation assessed by Principal coordinates analysis (PCoA). PCoA was based on the Bray–Curtis dissimilarity matrix of square-root transformed relative abundances of bacterial species. Bacterial communities defined by the sampling day and VAP occurrence were grouped to centroids. For this analysis of centroids, patient 1 was considered “non-VAP” as the VAP occurred on day 7 (late VAP). Difference was not significant on day 1 (PERMANOVA p > 0.05). D = day post-intubation
See this image and copyright information in PMC

References

    1. Vincent J-L, Sakr Y, Singer M, et al. Prevalence and outcomes of infection among patients in Intensive Care Units in 2017. JAMA. 2020;323:1478–1487. doi: 10.1001/jama.2020.2717. - DOI - PMC - PubMed
    1. Fenn D, Abdel-Aziz MI, van Oort PM, et al. Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia. Crit Care. 2022;26:203. doi: 10.1186/s13054-022-04068-z. - DOI - PMC - PubMed
    1. Woo S, Park S-Y, Kim Y, et al. The dynamics of respiratory microbiota during mechanical ventilation in patients with pneumonia. J Clin Med. 2020;9:E638. doi: 10.3390/jcm9030638. - DOI - PMC - PubMed
    1. Emonet S, Lazarevic V, Leemann Refondini C, et al. Identification of respiratory microbiota markers in ventilator-associated pneumonia. Intensive Care Med. 2019;45:1082–1092. doi: 10.1007/s00134-019-05660-8. - DOI - PMC - PubMed
    1. Dickson RP, Schultz MJ, van der Poll T, et al. Lung microbiota predict clinical outcomes in critically ill patients. Am J Respir Crit Care Med. 2020;201:555–563. doi: 10.1164/rccm.201907-1487OC. - DOI - PMC - PubMed

LinkOut - more resources