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. 2023 Jun 7:10:1184322.
doi: 10.3389/fsurg.2023.1184322. eCollection 2023.

Appendiceal collision tumors: case reports, management and literature review

Giovanni Viel #  1 , Francesco A Ciarleglio #  1 , Marco Frisini #  1 , Stefano Marcucci #  1 , Stefano Valcanover #  1 , Emma Bragantini #  2 , Mattia Barbareschi #  2 , Liliana Mereu #  3 , Saverio Tateo #  3 , Elettra Merola  4 , Franco Armelao #  4 , Giovanni De Pretis #  4 , Marco Brolese #  5 , Nicola L Decarli #  2 , Alberto Brolese  1
Affiliations

Appendiceal collision tumors: case reports, management and literature review

Giovanni Viel et al. Front Surg. .

Abstract

Appendiceal tumors are incidentally detected in 0.5% cases of appendectomy for acute appendicitis and occur in approximately 1% of all appendectomies. Here, we report two cases of appendiceal collision tumors in two asymptomatic women. In both cases, imaging revealed right-lower-quadrant abdominal masses, which were laparoscopically resected. In both cases, histological examinations revealed an appendiceal collision tumor comprising a low-grade appendiceal mucinous neoplasm and well-differentiated neuroendocrine neoplasm (NEN). For complete oncological control, right hemicolectomy was performed in one patient for the aggressive behavior of NEN; however, histology revealed no metastasis. The other patient only underwent appendectomy. No further treatment was recommended. According to the latest guidelines, exact pathology needs to be defined. Proper management indicated by a multidisciplinary team is fundamental.

Keywords: appendectomy; appendiceal tumors; collision tumor; low-grade appendiceal mucinous neoplasm; neuroendocrine neoplasm NEN.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(A,B): Abdominal MR T1 and T2-weighted images. (C): LAMN and NEN (red circle), hematoxylin and eosin (H & E) staining 10×. (D): Immunohistochemistry positive for Cg A. (E): Immunohistochemistry for Ki-67: proliferation index of 0.4%.
Figure 2
Figure 2
(A,B): abdominal MR T2- and T1-weighted images. (C): LAMN (red arrow) and NEN G1 (black arrow), (hematoxylin and eosin (H & E) staining).
See this image and copyright information in PMC

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