Effectiveness of concurrent exercise training in people with type 2 diabetes: A systematic review and meta-analysis

Abstract

Background: Concurrent Exercise Training (CET) is defined as an exercise training mode in which aerobic and resistance exercises are performed in the same session.

Objectives: The effects of CET in type 2 diabetes mellitus (T2DM) are inconclusive. Therefore, the objective of the present systematic review with a meta-analysis is to evaluate the effects of CET on metabolic markers, body composition, lipid profile, inflammation, and cardiorespiratory fitness (CRF) in people with T2DM.

Methods: Five electronic databases were searched from inception up to January 2023. The eligibility criteria included prospective studies that had T2DM participants aged between 35 and 65 years who performed CET at least 2 times/week for a minimum duration of 8 weeks with a control group.

Results: Seven studies were identified for qualitative review. Sufficient data were not available for one study, therefore, meta-analysis was performed in six studies. A significant effect was observed in glucose level (p < .01); glycated hemoglobin (p = .02); Homeostatic Model Assessment for Insulin Resistance (p = .02); body mass index (p = .02); %body fat (p < .01); %fat-free mass (p < .01); waist circumference (p = .03); triglyceride (p < .01); peak oxygen uptake (p < .01); and tumor necrotic factor -α (p < .01).

Conclusions: The CET is effective in improving metabolic markers, body composition, lipid profile, inflammation, and CRF in people with T2DM and can be included in the management of T2DM. The overall evidence for this conclusion may be influenced by bias in included studies.

Keywords: Same session combined training; diabetes mellitus; endurance training; glycated hemoglobin; strength training.