Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun 23;23(1):287.
doi: 10.1186/s12886-023-03047-4.

Assessment of anxiety and depression in patients with Posner-Schlossman syndrome

Chaoxu Qian  1 , Zhi Da Soh  2   3 , Sahil Thakur  2 , Wen Yan  4 , Xian Shao  4 , Hua Zhong #  4 , Kaidi Wang #  5
Affiliations

Assessment of anxiety and depression in patients with Posner-Schlossman syndrome

Chaoxu Qian et al. BMC Ophthalmol. .

Abstract

Background: To assess the anxiety and depression levels in patients with Posner-Schlossman syndrome (PSS) and to determine the potential risk factors.

Methods: In this cross-sectional study, a total of 195 participants, including 93 PSS patients and 102 healthy controls were recruited. Sociodemographic and clinical information were collected for all participants. Hospital Anxiety and Depression scale (HADS) was administered to evaluate the anxiety and depression levels. Visual function (VF) and quality-of-life (QOL) questionnaires were administered to assess variables potentially associated with anxiety and depression.

Results: Increased anxiety level was observed in 22 (23.7%) PSS patients as compared to 10 (9.8%) of controls (P = 0.009). While the frequency of depression between the two groups was not significantly different (P = 0.349). The mean anxiety and depression scores were 6.98 ± 4.20 and 6.44 ± 3.66 in PSS patients as compared to 6.67 ± 3.21 (P = 0.564) and 5.96 ± 2.93 (P = 0.311) in controls. Logistic regression analysis showed mental well-being was significantly associated with anxiety (odds ratio [OR] = 0.920, 95% confidence interval [CI] = 0.881-0.962, P < 0.001) and depression (OR = 0.959, CI = 0.926-0.994, P = 0.023) in PSS patients.

Conclusion: More patients with PSS may experience anxiety as compared to healthy controls. Mental well-being is an independent risk factor for anxiety and depression. It is important for ophthalmologists to be aware of these factors and should pay more attention on mental health when PSS is managed in clinic.

Keywords: Hospital anxiety and Depression scale; Posner-Schlossman syndrome; Vision-related quality of life.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Histograms of anxiety and depression in PSS patients and healthy controls. (A) The histograms of average scores for anxiety and depression of PSS patients and healthy controls. (B) The histograms of frequency of individual with anxiety and depression of PSS patients and healthy controls. *: P = 0.009
See this image and copyright information in PMC

References

    1. Jiang JH, Zhang SD, Dai ML, et al. Posner-Schlossman syndrome in Wenzhou, China: a retrospective review study. Br J Ophthalmol. 2017;101(12):1638–42. doi: 10.1136/bjophthalmol-2016-309863. - DOI - PubMed
    1. Okonkwo ON, Tripathy K. Posner Schlossman Syndrome. StatPearls. Treasure Island (FL)2022. - PubMed
    1. Kim JH, Lee JY, Choi JA. Long-term prognosis for glaucoma in patients with Posner-Schlossman syndrome. Graefe’s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 2021;259(12):3757–67. - PubMed
    1. Kong X, Yan M, Sun X, et al. Anxiety and depression are more prevalent in primary Angle Closure Glaucoma Than in Primary Open-Angle Glaucoma. J Glaucoma. 2015;24(5):e57–63. doi: 10.1097/IJG.0000000000000025. - DOI - PubMed
    1. Can Sandikci S, Colak S, Omma A, et al. An evaluation of depression, anxiety and fatigue in patients with Behcet’s disease. Int J Rheum Dis. 2019;22(6):974–9. doi: 10.1111/1756-185X.13411. - DOI - PubMed