Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2024 Jan;112(1):272-278.
doi: 10.1007/s10266-023-00828-7. Epub 2023 Jun 24.

Evaluation of the effect of different desensitizers on pulpal blood flow after full crown preparation using laser Doppler flowmetry: a randomized clinical trial

Zeliha Uğur-Aydın  1 , Hamiyet Kılınç  2 , Yasemin Akbaş  2 , Sıla Nur Usta  3
Affiliations
Randomized Controlled Trial

Evaluation of the effect of different desensitizers on pulpal blood flow after full crown preparation using laser Doppler flowmetry: a randomized clinical trial

Zeliha Uğur-Aydın et al. Odontology. 2024 Jan.

Abstract

This study aims to evaluate the effect of Teethmate, Bifluoride 12, and Copal Varnish on the treatment of dentin hypersensitivity and the pulpal blood flow using laser Doppler flowmetry (LDF) after full crown preparations. Eighteen patients with 42 teeth with dentine hypersensitivity after full crown preparations were randomly treated with Teethmate, Bifluoride 12, and Copal Varnish. Dentine hypersensitivity was measured using a visual analog scale (VAS) and Schiff air index (SAI). LDF was used to assess the pulpal blood flow and results were recorded in perfusion units (PU). All measurements were performed at baseline, 5 min, 7 days, and 1 month after the application of desensitizers. Data were statistically analyzed by Wilcoxon and two-way ANOVA tests (p < 0.05). There was no significant difference between the tested desensitizers regarding VAS and PU values. VAS values decreased significantly at 7 days and 1 month after the application of desensitizers compared to baseline in all groups. The decrease in PU values significantly differed only in the Copal Varnish group at 5 min and 7 days after the application of the desensitizer (p < 0.05). A statistically significant difference was found between different times regarding SAI scores in all groups (p < 0.05). Teethmate, Bifluoride 12, and Copal Varnish showed similar effectiveness on dentine hypersensitivity and pulpal blood flow. Long-term clinical trials with larger sample sizes and histological studies are needed to evaluate their impacts on pulpal status.

Keywords: Dentin hypersensitivity; Desensitizer; Laser Doppler flowmetry; Pulpal blood flow.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Orchardson R, Collins WJ. Clinical features of hypersensitive teeth. Br Dent J. 1987;162:253–6. - PubMed - DOI
    1. Kim SY, Kim EJ, Kim DS, et al. The evaluation of dentinal tubule occlusion by desensitizing agents: a real-time measurement of dentinal fluid flow rate and scanning electron microscopy. Oper Dent. 2013;38:419–28. - PubMed - DOI
    1. Davis GR, Tayeb RA, Seymour KG, et al. Quantification of residual dentine thickness following crown preparation. J Dent. 2012;40:571–6. - PubMed - DOI
    1. Richardson D, Tao L, Pashley DH. Dentin permeability: effects of crown preparation. Int J Prosthodont. 1991;4:219–25. - PubMed
    1. Bagis B, Atilla P, Cakar N, et al. Immunohistochemical evaluation of endothelial cell adhesion molecules in human dental pulp: effects of tooth preparation and adhesive application. Arch Oral Biol. 2007;52:705–11. - PubMed - DOI

Publication types

LinkOut - more resources