Development of Meropenem Resistance in a Multidrug-Resistant Campylobacter coli Strain Causing Recurrent Bacteremia in a Hematological Malignancy Patient
- PMID: 37358413
- PMCID: PMC10648861
- DOI: 10.1128/aac.00272-23
Development of Meropenem Resistance in a Multidrug-Resistant Campylobacter coli Strain Causing Recurrent Bacteremia in a Hematological Malignancy Patient
Abstract
Campylobacter bacteremia is an uncommon disease that mainly occurs in immunocompromised patients and is associated with antibiotic resistance, particularly in Campylobacter coli. We report a patient with persistent blood infection because of a multidrug-resistant (MDR) C. coli strain over a 3-month period. Through this period monotherapy with meropenem was associated with the development of resistance to it. Improving immunity status and a combined therapy for intestinal decolonization were useful to control persistent C. coli infection in this patient.
Keywords: Campylobacter coli; bloodstream infection; bloodstream infections; hematological patient; meropenem; multidrug resistance; multidrug resistant; whole-genome sequencing (WGS).
Conflict of interest statement
The authors declare no conflict of interest.
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Comment in
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Case Commentary: An espresso, a free puppy, and multidrug-resistant Campylobacter.Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0075223. doi: 10.1128/aac.00752-23. Epub 2023 Oct 12. Antimicrob Agents Chemother. 2023. PMID: 37823639 Free PMC article.
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