Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 May 12:37:103-105.
doi: 10.1016/j.jdcr.2023.05.001. eCollection 2023 Jul.

Effects of dupilumab on keloid stabilization and prevention

Ashley Wittmer  1 , Lindsey Finklea  2 , Jonathan Joseph  3
Affiliations
Case Reports

Effects of dupilumab on keloid stabilization and prevention

Ashley Wittmer et al. JAAD Case Rep. .
No abstract available

Keywords: acne; case reports; dupilumab; general dermatology; keloid; scar.

PubMed Disclaimer

Conflict of interest statement

Dr Finklea has been a consultant, speaker, or investigator for the following companies: Sanofi, Regeneron, and AbbVie.

Figures

Fig 1
Fig 1
Keloids. Patient’s left and right shoulders failing multiple attempts of intralesional triamcinolone.
Fig 2
Fig 2
Keloids. Patient’s shoulders following bilateral excision, grafting, and radiation. Patient’s right shoulder failing radiation with active inflammation, tenderness, and pruritus.
Fig 3
Fig 3
Keloids. Patient’s left and right shoulders after treatment with dupilumab.
Fig 4
Fig 4
Keloids. Patient’s right shoulder after 2 months of dupilumab treatment (left) and then after 5 months of dupilumab (right).
See this image and copyright information in PMC

References

    1. Ogawa R. Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis. Int J Mol Sci. 2017;18(3):606. doi: 10.3390/ijms18030606. - DOI - PMC - PubMed
    1. Ekstein S.F., Wyles S.P., Moran S.L., Meves A. Keloids: a review of therapeutic management. Int J Dermatol. 2021;60(6):661–671. doi: 10.1111/ijd.15159. - DOI - PMC - PubMed
    1. Alster T.S., Tanzi E.L. Hypertrophic scars and keloids: etiology and management. Am J Clin Dermatol. 2003;4(4):235–243. doi: 10.2165/00128071-200304040-00003. - DOI - PubMed
    1. Huang C., Liu L., You Z., Du Y., Ogawa R. Managing keloid scars: from radiation therapy to actual and potential drug deliveries. Int Wound J. 2019;16(3):852–859. doi: 10.1111/iwj.13104s. - DOI - PMC - PubMed
    1. Diaz A., Tan K., He H., et al. Keloid lesions show increased IL-4/IL-13 signaling and respond to Th2-targeting dupilumab therapy. J Eur Acad Dermatol Venereol. 2020;34(4):e161–e164. doi: 10.1111/jdv.16097. - DOI - PubMed

Publication types

LinkOut - more resources