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Case Reports
. 2023 Mar 24;9(6):381-385.
doi: 10.1016/j.hrcr.2023.03.011. eCollection 2023 Jun.

First human implant of the cardiac contractility modulation in patient with dilated cardiomyopathy-related laminopathy

Antonio D'Onofrio  1 , Giuseppe Palmiero  2 , Giuliano D'Alterio  1 , Stefano De Vivo  1 , Benedicta Maione  3 , Silvia Leonardi  3
Affiliations
Case Reports

First human implant of the cardiac contractility modulation in patient with dilated cardiomyopathy-related laminopathy

Antonio D'Onofrio et al. HeartRhythm Case Rep. .
No abstract available

Keywords: Cardiac contractility modulation; Cardiomyopathy; Electrical heart failure treatment; Heart failure; Laminopathy.

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Figures

Figure 1
Figure 1
Chest radiograph of the patient. The figure shows cardiac contractility modulation (CCM) device on the right side and implantable cardioverter-defibrillator (ICD) DR on the left side. DX indicates right site; DR indicates a dual chamber device. Adx lead = right atrial lead for ICD; CCM1-RV = lead reference ventricular CCM; CCM2-LS = lead local sense CCM; ICD lead = right ventricular lead for ICD.
Figure 2
Figure 2
A: Comparison between baseline echo and echo at 12 months follow-up. B: Myocardial work analysis between baseline and 12 months follow-up. LVEDV = left ventricular end-diastolic volume; LVEF = left ventricular ejection fraction; LVESV = left ventricular end-systolic volume.
Supplemental Video 1
Supplemental Video 1
Echo Exam Baseline 2-Chamber view1
Supplemental Video 2
Supplemental Video 2
Echo Exam Baseline 4-Chamber view2
Supplemental Video 3
Supplemental Video 3
Echo Exam 12 months FU 2-Chamber view3
Supplemental Video 4
Supplemental Video 4
Echo Exam 12 months FU 4-Chamber view4
See this image and copyright information in PMC

References

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    1. Peretto G., Sala S., Benedetti S., et al. Updated clinical overview on cardiac laminopathies: an electrical and mechanical disease. Nucleus. 2018;9:380–391. - PMC - PubMed
    1. Parks S.B., Kushner J.D., Nauman D., et al. Lamin A/C mutation analysis in a cohort of 324 unrelated patients with idiopathic or familiar dilated cardiomyopathy. Am Heart J. 2008;156:161–169. - PMC - PubMed

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