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Review
. 2023 Apr 11;3(3):212-219.
doi: 10.1016/j.jointm.2023.02.003. Online ahead of print.

Is COVID-19 different from other causes of acute respiratory distress syndrome?

François M Beloncle  1
Affiliations
Review

Is COVID-19 different from other causes of acute respiratory distress syndrome?

François M Beloncle. J Intensive Med. .

Abstract

Coronavirus disease 2019 (COVID-19) pneumonia can lead to acute hypoxemic respiratory failure. When mechanical ventilation is needed, almost all patients with COVID-19 pneumonia meet the criteria for acute respiratory distress syndrome (ARDS). The question of the specificities of COVID-19-associated ARDS compared to other causes of ARDS is of utmost importance, as it may justify changes in ventilatory strategies. This review aims to describe the pathophysiology of COVID-19-associated ARDS and discusses whether specific ventilatory strategies are required in these patients.

Keywords: Dead space; Gas exchange; Mechanical ventilation; Recruitability; Respiratory mechanics.

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Conflict of interest statement

The author declares that he has no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

References

    1. COVID-ICU Group on behalf of the REVA Network and the COVID-ICU Investigators Clinical characteristics and day-90 outcomes of 4244 critically ill adults with COVID-19: a prospective cohort study. Intensive Care Med. 2021;47(1):60–73. doi: 10.1007/s00134-020-06294-x. - DOI - PMC - PubMed
    1. Definition Task Force A.R.D.S., Ranieri V.M., Rubenfeld G.D., Thompson B.T., Ferguson N.D., Caldwell E., et al. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012;307(23):2526–2533. doi: 10.1001/jama.2012.5669. - DOI - PubMed
    1. Ashbaugh D.G., Bigelow D.B., Petty T.L., Levine B.E. Acute respiratory distress in adults. Lancet. 1967;2(7511):319–323. doi: 10.1016/s0140-6736(67)90168-7. - DOI - PubMed
    1. Gattinoni L., Marini J.J., Pesenti A., Quintel M., Mancebo J., Brochard L. The "baby lung" became an adult. Intensive Care Med. 2016;42(5):663–673. doi: 10.1007/s00134-015-4200-8. - DOI - PubMed
    1. Ferguson N.D., Fan E., Camporota L., Antonelli M., Anzueto A., Beale R., et al. The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med. 2012;38(10):1573–1582. doi: 10.1007/s00134-012-2682-1. - DOI - PubMed