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Clinical Trial
. 1979 Feb;38(1):36-9.
doi: 10.1136/ard.38.1.36.

A thermographic and clinical comparison of three intra-articular steroid preparations in rheumatoid arthritis

H A Bird, E F Ring, P A Bacon
Clinical Trial

A thermographic and clinical comparison of three intra-articular steroid preparations in rheumatoid arthritis

H A Bird et al. Ann Rheum Dis. 1979 Feb.

Abstract

We have compared three intra-articular steroid preparations in a double blind study on 30 patients with rheumatoid arthritis and bilateral synovitis of the knees. One knee was injected with 1.0 ml of either prednisolone t-butyl acetate, methyl prednisolone acetate, or triamcinolone hexacetonide, and the patients were followed up for 6 weeks with regular clinical and thermographic assessments. Thermographic improvement was seen with all 3 drugs but was greatest initially and longest lasting with triamcinolone. No significant systemic improvement was seen with any drug after a single injection, though all 3 steroid preparations suppressed endogenous cortisol.

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References

    1. J Clin Pathol. 1962 Jul;15:374-9 - PubMed
    1. Ohio Med. 1957 Jan;53(1):45-6 - PubMed
    1. J Am Med Assoc. 1951 Dec 22;147(17):1629-35 - PubMed
    1. Curr Med Res Opin. 1977;5(2):141-6 - PubMed
    1. Br J Clin Pharmacol. 1978 May;5(5):447-51 - PubMed