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. 2023 Jul;44(4):261-274.
doi: 10.1007/s00292-023-01204-6. Epub 2023 Jun 27.

[Basic nephropathology for pathologists-part 2 : Non-inflammatory lesions]

[Article in German]
Ariana Gaspert  1 , Maike Büttner-Herold  2 , Kerstin Amann  2
Affiliations

[Basic nephropathology for pathologists-part 2 : Non-inflammatory lesions]

[Article in German]
Ariana Gaspert et al. Pathologie (Heidelb). 2023 Jul.

Abstract
in English, German

The evaluation of kidney biopsies for specific renal diseases or kidney transplant biopsies is mainly restricted to specialized centers. Lesions in nonneoplastic renal tissue in partial nephrectomies or nephrectomies due to renal tumors, especially noninflammatory, ischemic, vascular changes or diabetic nephropathy can be of greater prognostic significance than the tumor itself in patients with a localized tumor and good tumor-associated survival. In this part of basic nephropathology for pathologists, the most common noninflammatory lesions of the vascular, glomerular and tubulo-interstitial compartment are discussed.

Die Nierenbiopsiediagnostik bei medizinisch indizierten Biopsien und Nierentransplantatbiopsien wird überwiegend in Zentren mit ausgebildeten Nephropathologen betrieben. Veränderungen im nichtneoplastischen Nierenparenchym bei tumorbedingten Nephrektomien, insbesondere nichtentzündliche, ischämisch und vaskulär bedingte Veränderungen oder diabetische Nephropathie, können bei Patienten mit lokalisiertem Nierenkarzinomen und gutem tumorassoziiertem Überleben prognostisch von größerer Bedeutung sein als das Tumorleiden an sich. In diesem Teil zu den Grundlagen der Nierenpathologie für Pathologen sollen die häufigsten nichtentzündlichen Nierenerkrankungen im vaskulären, glomerulären und tubulointerstitiellen Kompartiment beleuchtet werden.

Keywords: Diabetic nephropathy; Differential diagnosis; Hypertension; Nephropathy; Thrombotic microangiopathy.

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