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Case Reports
. 2023 Jun 9;12(6):1033.
doi: 10.3390/antibiotics12061033.

First Case of VIM-1-like-Producing Pseudomonas putida Bacteremia in an Oncohematological Pediatric Patient in Italy

Venere Cortazzo  1 , Marilena Agosta  1 , Stefania Gaspari  2 , Gianluca Vrenna  1 , Barbara Lucignano  1 , Manuela Onori  1 , Valentina Di Ruscio  2 , Livia Mancinelli  1 , Danielle Domo  1   3 , Carlo Federico Perno  1 , Paola Bernaschi  1
Affiliations
Case Reports

First Case of VIM-1-like-Producing Pseudomonas putida Bacteremia in an Oncohematological Pediatric Patient in Italy

Venere Cortazzo et al. Antibiotics (Basel). .

Abstract

Bacterial infections caused by multidrug-resistant (MDR) Gram-negatives are of great concern worldwide, as they are frequently associated with high mortality and morbidity rates. To date, two cases of VIM-2 metallo-β-lactamase (MBL)-producing Pseudomonas putida bacteremia have been ever reported in France and Spain between 2004 and 2010. Here, we present the first case of VIM-1-like-producing P. putida isolated in blood culture collected from an oncohematological pediatric patient admitted to Bambino Gesù Children's Hospital (IRCCS) in Rome, Italy.

Keywords: Pseudomonas putida; VIM-1-like; metallo-β-lactamases; multidrug-resistant; pediatric patient; polymicrobial bacteremia.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Perianal lesion on day 1 (a) and day 50 (b) of hospitalization.
Figure 2
Figure 2
Timeline of microbiological investigations and relevant findings, starting from the fifth day of patient hospitalization (created with BioRender.com, accessed on 29 May 2023. Reproduction of this figure requires permission from Bio.Render.com). Abbreviations: BCID2, BioFire FilmArray blood culture identification 2.
Figure 3
Figure 3
Agarose gel electrophoresis image of the studied sample (blaVIM size 390 bp). bp, base pairs; +, positive; −, negative.
See this image and copyright information in PMC

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