Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases
- PMID: 373707
- DOI: 10.1007/BF00296896
Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases
Similar articles
-
Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.Carcinogenesis. 1993 Jul;14(7):1271-8. doi: 10.1093/carcin/14.7.1271. Carcinogenesis. 1993. PMID: 8330339
-
Covalent binding in vitro of polychlorinated biphenyls to microsomal macromolecules. Involvement of metabolic activation by a cytochrome P-450-linked mono-oxygenase system.Biochem Pharmacol. 1978 Feb 15;27(4):585-93. doi: 10.1016/0006-2952(78)90399-4. Biochem Pharmacol. 1978. PMID: 204312 No abstract available.
-
Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.Arch Biochem Biophys. 1994 Jun;311(2):342-9. doi: 10.1006/abbi.1994.1246. Arch Biochem Biophys. 1994. PMID: 8203896
-
Mutagenicity and metabolism of vinyl chloride and related compounds.Environ Health Perspect. 1976 Oct;17:193-8. doi: 10.1289/ehp.7617193. Environ Health Perspect. 1976. PMID: 799962 Free PMC article. Review.
-
Developmental aspects of the hepatic cytochrome P450 monooxygenase system.Annu Rev Pharmacol Toxicol. 1976;16:427-45. doi: 10.1146/annurev.pa.16.040176.002235. Annu Rev Pharmacol Toxicol. 1976. PMID: 820239 Review. No abstract available.
Cited by
-
Extended Analysis and Evidence Integration of Chloroprene as a Human Carcinogen.Risk Anal. 2020 Feb;40(2):294-318. doi: 10.1111/risa.13397. Epub 2019 Sep 16. Risk Anal. 2020. PMID: 31524302 Free PMC article. Review.
-
Review of epidemiologic study results of vinyl chloride-related compounds.Environ Health Perspect. 1981 Oct;41:221-6. doi: 10.1289/ehp.8141221. Environ Health Perspect. 1981. PMID: 7333239 Free PMC article.
-
Results of NTP-sponsored mouse cytogenetic studies on 1,3-butadiene, isoprene, and chloroprene.Environ Health Perspect. 1990 Jun;86:71-3. doi: 10.1289/ehp.908671. Environ Health Perspect. 1990. PMID: 2401274 Free PMC article.
-
Investigations on metabolism, genotoxic effects and carcinogenicity of 2,2'-dichlorodiethylether.J Cancer Res Clin Oncol. 1986;112(2):125-30. doi: 10.1007/BF00404394. J Cancer Res Clin Oncol. 1986. PMID: 3771621 Free PMC article.
-
Molecular electrostatic potentials: an effective tool for the elucidation of biochemical phenomena.Environ Health Perspect. 1985 Sep;61:191-202. doi: 10.1289/ehp.8561191. Environ Health Perspect. 1985. PMID: 2866089 Free PMC article. Review.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources