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. 2023 Jun 14;59(6):1143.
doi: 10.3390/medicina59061143.

Etiology and Multi-Drug Resistant Profile of Bacterial Infections in Severe Burn Patients, Romania 2018-2022

Bogdan Nițescu  1   2 , Daniela Pițigoi  1   3 , Daniela Tălăpan  1   3 , Maria Nițescu  1   3 , Sorin Ștefan Aramă  1   4 , Bogdan Pavel  1   2 , Adrian Streinu-Cercel  1   3 , Alexandru Rafila  1   3 , Victoria Aramă  1   3
Affiliations

Etiology and Multi-Drug Resistant Profile of Bacterial Infections in Severe Burn Patients, Romania 2018-2022

Bogdan Nițescu et al. Medicina (Kaunas). .

Abstract

Infections in severe burns and their etiology are and will remain a big concern for the medical field. The multi-drug resistant strains of bacteria are a challenge of today's medicine. The aim of our study was to identify the etiological spectrum of bacterial infections in severe burn patients in Romania and their multi-drug resistant patterns. We performed a prospective study that included 202 adult patients admitted to the intensive care unit (ICU) of the Clinical Emergency Hospital of Plastic, Reconstructive Surgery and Burns, Bucharest, Romania (CEHPRSB), from 1 October 2018 to 1 April 2022, a period which includes the first 2 years of the outbreak of COVID-19. From each patient, wound swabs, endotracheal aspirates, blood for blood culture, and urine were collected. The most frequently isolated bacterium was Pseudomonas aeruginosa (39%), followed by Staphylococcus aureus (12%), Klebsiella spp. (11%), and Acinetobacter baumannii (9%). More than 90% of Pseudomonas aeruginosa and Acinetobacter baumannii were MDR, regardless of the clinical specimen from which they were isolated.

Keywords: Pseudomonas aeruginosa; bacterial infections; burns; multi-drug resistance; wound infections.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Model of sample collection according to the ICU protocol of CEHPRSB.
Figure 2
Figure 2
The frequency of isolated microorganisms.
Figure 3
Figure 3
The percentage of MDR strains among each main pathogenic bacterium isolated.
Figure 4
Figure 4
Comparison of colistin resistance among the main Gram-negative rods isolated.
See this image and copyright information in PMC

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