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Review
. 2023 Nov;34(6):542-550.
doi: 10.1111/cyt.13263. Epub 2023 Jun 28.

Cystic lesions in the salivary gland. Pitfalls to be avoided on cytology

Federica Vegni  1 , Angela Feraco  1 , Federica Policardo  1 , Pietro Tralongo  1 , Ilenia De Stefano  1 , Giulia Ferraro  1 , Qianqian Zhang  1 , Angela Carlino  1 , Elena Navarra  1 , Antonino Mulè  1 , Esther Diana Rossi  1
Affiliations
Review

Cystic lesions in the salivary gland. Pitfalls to be avoided on cytology

Federica Vegni et al. Cytopathology. 2023 Nov.

Abstract

Cystic lesions of the salivary glands are very uncommon entities. However, on occasion, some neoplasms of the salivary glands show a cystic component, which may be predominant or only partially cystic. Basal cell adenoma, canalicular adenoma, oncocytoma, sebaceous adenoma, intraductal papilloma, epithelial-myoepithelial carcinoma, intraductal carcinoma, and secretory carcinoma are such cystic entities. Cystic degeneration and necrosis, which can develop within solid tumours, represent another possibility. The ability to recognise this type of lesion is a challenge in diagnostic cytology because hypocellular fluid is frequently recovered. Furthermore, evaluating all of the differential diagnoses for cystic lesions of the salivary glands is helpful in obtaining the correct diagnosis. Herein, we evaluate the various types of cystic lesions within the salivary glands.

Keywords: cystic lesions; fine needle aspiration cytology; immunocytochemistry; personalised medicine; salivary glands.

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References

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