Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2023 Jun 23:31:e20230025.
doi: 10.1590/1678-7757-2023-0025. eCollection 2023.

Clinical performance of an alkasite-based bioactive restorative in class II cavities: a randomized clinical trial

Fatma Dilsad Oz  1 , Ece Meral  1 , Sevil Gurgan  1
Affiliations
Randomized Controlled Trial

Clinical performance of an alkasite-based bioactive restorative in class II cavities: a randomized clinical trial

Fatma Dilsad Oz et al. J Appl Oral Sci. .

Abstract

Objective: This clinical study aimed to evaluate the clinical performance of an alkasite-based bioactive material by comparing it with a resin composite (RC) in the restoration of Class II cavities over a year.

Methodology: A hundred Class II cavities were restored at 31 participants. Groups were as follows: Cention N (CN) (Ivoclar Vivadent, Schaan, Liechtenstein) and G-ænial Posterior (GP) (GC, Tokyo, Japan) in combination with G-Premio Bond (etch&rinse). Restorative systems were applied following manufacturers' instructions. They were finished and polished immediately after placement and scored based on retention, marginal discoloration, marginal adaptation, sensitivity, surface texture, and color match using modified USPHS criteria after 1 week (baseline), 6 months, and 12 months. Statistical analyses were performed using chi-square, McNemar's, and Kaplan Meier tests.

Results: After 12 months, the recall rate was 87%. Survival rates of CN and GP restorations were 92.5% and 97.7%, respectively. Three CN and one GP restorations lost retention. Seven CN (17.9%) and five (11.6%) GP restorations were scored as bravo for marginal adaptation and no significant difference was seen between groups (p=0.363). One (2.7%) CN and two GP (4.7%) restorations were scored as bravo for marginal discoloration, but no significant difference was observed between groups(p=1.00). For surface texture, three (8.1%) CN and three (7%) GP restorations were scored as bravo (p=1.00). None of the restorations demonstrated post-operative sensitivity or secondary caries at any examinations.

Conclusion: The tested restorative materials performed similar successful clinical performances after 12 months. ClinicalTrials.gov (NTC04825379).

PubMed Disclaimer

Conflict of interest statement

Conflict of interest

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1. Inclusion and exclusion criteria for participants
Figure 2
Figure 2. Applications of materials used in the study
MDP: 10-Methacryloyloxydecyl dihydrogen phosphate, Bis-GMA: Bisphenol A diglycidylmethacrylate, HEMA: 2-Hydroxyethyl methacrylate, BHT: Butylated hydroxytoluene, MDTP: Methacryloyloxydecyl dihydrogen thiophosphate
Figure 3
Figure 3. Flow diagram of the study
Figure 4
Figure 4. Survival curves for tested groups (CN [Cention N], GP [G- ænial Posterior])
See this image and copyright information in PMC

References

    1. Mejare I, Kallestal C, Stenlund H, Johansson H. Caries development from 11 to 22 years of age: a prospective radiographic study. Prevalence and distribution. Caries Res. 1998;32(1):10–16. doi: 10.1159/000016424. - DOI - PubMed
    1. Meyer-Lueckel H, Paris S. When and how to intervene in the caries process. Oper Dent. 2016;41(7):35–47. doi: 10.2341/15-022-O. - DOI - PubMed
    1. Nedeljkovic I, Teughels W, De Munck J, Van Meerbeek B, Van Landuyt KL. Is secondary caries with composites a material-based problem? Dent Mater. 2015;31(11):247–277. doi: 10.1016/j.dental.2015.09.001. - DOI - PubMed
    1. Wiegand A, Buchalla W, Attin T. Review on fluoride-releasing restorative materials - fluoride release and uptake characteristics, antibacterial activity and influence on caries formation. Dent Mater. 2007;23(3):343–362. doi: 10.1016/j.dental.2006.01.022. - DOI - PubMed
    1. Gurgan S, Kutuk ZB, Yalcin Cakir F, Ergin E. A randomized controlled 10 years follow up of a glass ionomer restorative material in class I and class II cavities. 103175J Dent. 2020;94 doi: 10.1016/10.1016/j.jdent.2019.07.013. - DOI - PubMed

Publication types