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Case Reports
. 2023 Jun;55(2):86-90.
doi: 10.1051/ject/2023007. Epub 2023 Jun 28.

Case Report: Congenital tuberculosis in a premature infant requiring extracorporeal membrane oxygenation

Hugh K Quach  1 , Briana L Scott  2 , Denise A Lopez-Domowicz  3 , Rachel M Gambino  4 , Amy E Evans  4 , Caroline P Ozment  2
Affiliations
Case Reports

Case Report: Congenital tuberculosis in a premature infant requiring extracorporeal membrane oxygenation

Hugh K Quach et al. J Extra Corpor Technol. 2023 Jun.

Abstract

Congenital tuberculosis is a rare infectious disease with less than 500 cases documented worldwide. Mortality is significant, ranging from 34 to 53%, and death without treatment is inevitable. Patients exhibit nonspecific symptoms such as fever, cough, respiratory distress, feeding intolerance, and irritability which can make appropriate diagnosis challenging in Peng et al. (2011) Pediatr Pulmonol 46(12), 1215-1224. Tuberculosis prevalence is particularly high in developing countries where access to resources can be limited in World Health Organization (2019) Global tuberculosis report 2019, Geneva. We present a 2.4-kg premature male infant with acute respiratory distress syndrome secondary to congenital tuberculosis caused by Mycobacterium bovis and tuberculosis-immune reconstitution inflammatory syndrome who was successfully supported with veno-arterial extracorporeal membrane oxygenation.

Keywords: Congenital tuberculosis; Extracorporeal membrane oxygenation; Mycobacterium bovis.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

Figure 1
Figure 1
Chest X-ray with diffuse alveolar and interstitial opacities, R > L, possibly representative of developing pneumonia/ARDS.
Figure 2
Figure 2
Timeline depicting clinical course of patient case.
See this image and copyright information in PMC

References

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