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. 2023 Jun;81(6):597-606.
doi: 10.1055/s-0043-1768676. Epub 2023 Jun 28.

Ketogenic therapy in childhood and adolescence: recommendations of the Brazilian experts group

Letícia Pereira de Brito Sampaio  1 , Adélia Maria de Miranda Henriques-Souza  2 , Katia Lin  3 , Lenycia de Cassya Lopes Neri  1 , Luciana Midori Inuzuka  4 , Ludmila Inácio de Lima Uchôa  5 , Marcela Marques de Oliveira Gregório  6 , Laura Maria Guilhoto  6   7 , Maria Augusta Montenegro  8 , Mariana Lunardi  9 , Marielza Veiga  10 , Patricia Azevedo de Lima  11 , Vera Braatz  12
Affiliations

Ketogenic therapy in childhood and adolescence: recommendations of the Brazilian experts group

Letícia Pereira de Brito Sampaio et al. Arq Neuropsiquiatr. 2023 Jun.

Abstract
in English, Portuguese

Ketogenic dietary therapies (KDTs) are a safe and effective treatment for pharmacoresistant epilepsy in children. There are four principal types of KDTs: the classic KD, the modified Atkins diet (MAD), the medium-chain triglyceride (MCT) diet, and the low glycemic index diet (LGID). The International Ketogenic Diet Study Group recommends managing KDTs in children with epilepsy. However, there are no guidelines that address the specific needs of the Brazilian population. Thus, the Brazilian Child Neurology Association elaborated on these recommendations with the goal of stimulating and expanding the use of the KD in Brazil.

As terapias dietéticas cetogênicas (TDC) são um tratamento seguro e eficaz para epilepsia farmacorresistente em crianças. Existem quatro tipos principais de TDCs: a dieta cetogênica (DC) clássica, a dieta de Atkins modificada (DAM), a dieta de triglicerídeos de cadeia média (DTCM) e a dieta de baixo índice glicêmico (DBIG). O Grupo Internacional de Estudos de Dietas Cetogênicas (International Ketogenic Diet Study Group) propõe recomendações para o manejo da DC em crianças com epilepsia. No entanto, faltam diretrizes que contemplem as necessidades específicas da população brasileira. Assim, a Associação Brasileira de Neurologia Infantil elaborou essas recomendações com o objetivo de estimular e expandir o uso da DC no Brasil.

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Conflict of interest statement

The authors have no conflict of interest to declare.

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