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Comment
. 2023 Sep;39(9):639-641.
doi: 10.1016/j.tig.2023.06.001. Epub 2023 Jun 26.

Decoding a ribosome uncertainty

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Decoding a ribosome uncertainty

Olivier Duss et al. Trends Genet. 2023 Sep.

Abstract

The ribosome is among the most ancient macromolecular complexes. Throughout evolution, the function of the ribosome has remained essential and conserved: the decoding of an mRNA template with tRNA-linked amino acids, to synthesize a protein. In a recent study, Holm et al. capture evolutionary distinctions in the structure and kinetics of 'mRNA decoding' by the human ribosome.

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Declaration of interests No interests are declared.

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