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Review
. 2023 Jun 13:10:1117071.
doi: 10.3389/fmed.2023.1117071. eCollection 2023.

Myositis interstitial lung disease and autoantibodies

Shire Chaudhry  1 , Lisa Christopher-Stine  2
Affiliations
Review

Myositis interstitial lung disease and autoantibodies

Shire Chaudhry et al. Front Med (Lausanne). .

Abstract

The aim of this review is to examine and evaluate published literature associated with idiopathic inflammatory myopathies (IIM) and interstitial lung disease (ILD) based on myositis specific autoantibodies (MSA) and the potential clinical significance of each autoantibody subtype for the practicing clinician. The review is a comprehensive search of literature published in PubMed from the year 2005 and onward coinciding with the surge in the discovery of new MSAs. Additionally, we comment on recommended multidisciplinary longitudinal care practices for patients with IIM-ILD with regard to imaging and other testing. Treatment is not covered in this review.

Keywords: interstitial lung disease; myositis; myositis specific autoantibodies; narrative review; pulmonary fibrosis.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Timeline of Myositis specific auto-antibodies. Adapted from Neil J. McHugh and Sarah L. Tansley.
Figure 2
Figure 2
MSA’s interposed onto the IIM’s; caution symbol denotes more severe disease when anti-Ro autoantibodies are present.
See this image and copyright information in PMC

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