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Case Reports
. 2023 May 28;15(5):e39611.
doi: 10.7759/cureus.39611. eCollection 2023 May.

A Rare Type of Hepatocellular Carcinoma Presenting With Cardiac Thrombus

Majd B Aboona  1 , Wendi Zhou  2 , Karn Wijarnpreecha  3   4
Affiliations
Case Reports

A Rare Type of Hepatocellular Carcinoma Presenting With Cardiac Thrombus

Majd B Aboona et al. Cureus. .

Abstract

Hepatocellular carcinoma (HCC) is a complication of end stage liver disease. Even rarer is right atrial tumor thrombus burden due to HCC. Common metastatic sites of HCC in descending order are lung, peritoneum, and bone. We present a patient with liver cirrhosis due to nonalcoholic fatty liver disease (NAFLD) admitted due to incidental finding of right atrial thrombus on echocardiography after missing HCC surveillance for four years. Patient received a computed tomography (CT) scan that showed an inconclusive liver lesion despite two liver biopsies, and patient was incidentally found to have clear cell HCC diagnosed after right hepatectomy. Right atrial thrombus was treated with surgical thrombectomy and pathology showed necrotic HCC thrombi in right atrium with bile pigment. Due to the possibility of tumor growth with extrahepatic manifestations, screening in compensated cirrhosis is essential.

Keywords: cirrhosis; hepatocellular carcinoma; hepatology; non alcoholic fatty liver; right atrial thrombus.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Computerized tomography (CT) scan showing a mass measuring 3.8x4.1x3.2 cm with slight peripheral nodular enhancement during the arterial phase.
Figure 2
Figure 2. Computerized tomography (CT) scan showing thrombus extending from the liver to the heart.
Figure 3
Figure 3. Necrotic hepatocellular carcinoma thrombi in right atrium with bile pigment. (Hematoxylin & Eosin, X 100)
Figure 4
Figure 4. Necrotic hepatocellular carcinoma thrombi in right atrium with bile pigment. (Hematoxylin & Eosin, X 400)
See this image and copyright information in PMC

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