Case of calcinosis cutis associated with Sjogren's syndrome

Abstract

Calcinosis cutis is a chronic condition involving skin and soft tissue deposition of calcium and phosphate. It is associated with several conditions including idiopathic, iatrogenic, malignant metastasis, calciphylaxis, and connective tissue diseases. The most common connective tissue diseases it is associated with include systemic sclerosis and dermatomyositis. We present a case image of a patient with Sjogren's syndrome and calcinosis cutis and its progression over time. The patient was optimized on her current treatment regimen to prevent further progression. Written informed consent was obtained from the patient to publish this report in accordance with the journal's patient consent policy.

Keywords: Sjogren's syndrome; calcinosis cutis; imaging; skin calcification.

FIGURE 1

Subcutaneous nodules in the right forearm.

FIGURE 2

X‐ray of the left knee, lateral view. (A) Mild calcification in the anterior to the distal quadriceps. (B) Progressive diffuse sheet‐like calcifications are anterior to the distal quadriceps 1 year after.

FIGURE 3

Posteroanterior view of the right hand. (A) Calcifications in PIP joints second to fifth and DIP joints second and fourth. (B) Progressive calcifications in the thumb, PIP joints second to fifth, and DIP joints second to fourth 2 years after.